News | BOOSTER >
First Booster-supported paper successfully published
Breakthrough study unveils plant gene regulatory networks (GRNs) with MINI-AC method
In a significant stride forward for plant genomics, BOOSTER partners Julia Engelhorn, Hilde Nelissen, and Thomas Hartwig, under the leadership of principal investigator Klaas Vandepoele of the VIB Ghent, in collaboration with other esteemed authors, have successfully published their paper titled “MINI-AC: Inference of Plant Gene Regulatory Networks Using Bulk or Single-Cell Accessible Chromatin Profiles” in The Plant Journal by the Society for Experimental Biology (SEB).
The research focuses on understanding gene regulatory networks (GRNs) in plants, which play vital roles in growth, development, and stress responses. Despite challenges in deciphering these networks, the study introduces MINI-AC, a method that combines accessible chromatin (AC) data with transcription factor binding site (TFBS) information to infer GRNs in plants. MINI-AC has been validated using datasets from Arabidopsis thaliana and successfully applied to maize, revealing regulatory interactions in leaf tissues. This demonstrates MINI-AC’s efficacy in identifying both general and cell-type-specific regulators, particularly in the context of C4 metabolism.
About IDConsortium
IDConsortium is a consultancy founded in Seville in 2009 with the aim of helping researchers and companies to internationalize and showcase their Research and Development (R&D) by joining international consortia to carry out different lines of research, development and innovation.
To date, it has successfully managed 22 European and national projects, worth more than €88 million in public funding. Currently, more than 250 European and international partners are part of its network.
For more information and press
Macarena Sanz
More news about BOOSTER:
BOOSTER field trials put promising maize biostimulants to the test under drought
BOOSTER partners launched new maize field trials across Europe to assess how selected biostimulant solutions can help crops cope with drought while supporting plant health and productivity.
EIAR advances BOOSTER field validation of microbial biostimulants for drought-stressed teff
One of EIAR contribution has been the successful development and optimisation of a protocol for the mass production of microbial biostimulants through seed coating, also known as pelleting.
New BOOSTER video now available!
The video features BOOSTER partners in action, showing where and how the work is carried out, and how collaboration drives progress across the project.